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Drug Transporters
Handbook of Experimental Pharmacology 201
ISBN/EAN: 9783642145407
Umbreit-Nr.: 1201209
Sprache:
Englisch
Umfang: x, 454 S.
Format in cm:
Einband:
gebundenes Buch
Erschienen am 04.01.2011
Auflage: 1/2011
- Zusatztext
- It is increasingly recognized that various transporter proteins are expressed throughout the body and determine absorption, tissue distribution, biliary and renal elimination of endogenous compounds and drugs and drug effects. This book will give an overview on the transporter families which are most important for drug therapy. Most chapters will focus on one transporter family highlighting tissue expression, substrates, inhibitors, knock-out mouse models and clinical studies.
- Kurztext
- This book provides a comprehensive overview of key drug transporters.It highlights mechanisms of drug absorption, elimination and drug-drug interactions and discusses the role of drug transporters for drug developmentIncludes supplementary material: sn.pub/extras