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GPCRs: From Deorphanization to Lead Structure Identification
Ernst Schering Foundation Symposium, Ernst Schering Foundation Symposium Proceedings 2006/2
ISBN/EAN: 9783540489818
Umbreit-Nr.: 1562142
Sprache:
Englisch
Umfang: xvii, 269 S.
Format in cm: 1.7 x 21.5 x 15
Einband:
gebundenes Buch
Erschienen am 03.07.2007
Auflage: 1/2007
- Zusatztext
- InhaltsangabeG Proteins and GPCR: From the Beginning.- Modelling GPCRs.- Privileged Structures in GPCRs.- Designing Compound Libraries Targeting GPCRs.- Virus-encoded G Protein Coupled Receptors: Constitutively Active (dys) Regulators of Cell Function and their Potential as Drug Target.- Modulation of GPCR Conformations by Ligands, G Proteins and Arrestins.- The Role of GPCR Dimerisation/Oligomerisation in Receptor Signalling.- Orphan Seven Transmembrane Receptor (7TMR) Screening.- High Content Screening to Monitor G Protein-Coupled Receptor Internalization.- High Throughput Lead Finding and Optimisation for GPCR Targets.