Detailansicht
Applied NMR Spectroscopy for Chemists and Life Scientists
ISBN/EAN: 9783527327751
Umbreit-Nr.: 4622781
Sprache:
Englisch
Umfang: 548 S., 220 s/w Illustr., 30 farbige Illustr., 250
Format in cm:
Einband:
gebundenes Buch
Erschienen am 04.12.2013
Auflage: 1/2013
- Zusatztext
- This application-oriented textbook covers theory and practice of modern NMR applications, from complex stucture elucidation to biomolecular interaction and reaction control. The author is a former co-worker of Nobel laureate Kurt Wüthrich.
- Kurztext
- From complex structure elucidation to biomolecular interactions - this applicationoriented textbook covers both theory and practice of modern NMR applications. Part one sets the stage with a general description of NMR introducing important parameters such as the chemical shift and scalar or dipolar couplings. Part two describes the theory behind NMR, providing a profound understanding of the involved spin physics, deliberately kept shorter than in other NMR textbooks, and without a rigorous mathematical treatment of all the physico-chemical computations. Part three discusses technical and practical aspects of how to use NMR. Important phenomena such as relaxation, exchange, or the nuclear Overhauser effects and the methods of modern NMR spectroscopy including multidimensional experiments, solid state NMR, and the measurement of molecular interactions are the subject of part four. The final part explains the use of NMR for the structure determination of selected classes of complex biomolecules, from steroids to peptides or proteins, nucleic acids, and carbohydrates. For chemists as well as users of NMR technology in the biological sciences.
- Autorenportrait
- Oliver Zerbe is the head of the NMR department at the University of Zurich. He studied chemistry and obtained his PhD under the supervision of Wolfgang von Philipsborn in Zurich. After a Postdoctoral stay in the group of Kurt Wüthrich at the ETH Zurich he conducted his Habilitation with Gerd Folkers at the Institute of Pharmaceutical Sciences at the ETH. In 2003 he returned to his present location at the University of Zurich, where is now is a professor in the Department of Chemistry. His main interests are structures of proteins, particularly of membrane proteins. Oliver Zerbe is the author of approx. 100 scientific publications in peer-reviewed journals and has edited one book, 'NMR in drug research'.