Detailansicht
T Lymphocytes as Tools in Diagnostics and Immunotoxicology
Experientia Supplementum 104
ISBN/EAN: 9783034807258
Umbreit-Nr.: 5549408
Sprache:
Englisch
Umfang: vi, 184 S., 6 s/w Illustr., 21 farbige Illustr., 1
Format in cm:
Einband:
gebundenes Buch
Erschienen am 21.11.2013
Auflage: 1/2013
- Zusatztext
- InhaltsangabeThe use of T cells in Hazard Characterization of Chemical and Drug Allergens and integration in testing strategies.- Activation of the TCR complex by peptide-MHC and superantigens.- Activation of the TCR complex by small chemical compounds.- T Cell Responses to Contact Allergens.- Contact hypersensitivity: Quantitative aspects, susceptibility and risk factors.- Tools and methods for identification and analysis of rare antigen-specific T lymphocytes.- Human T cell priming assay. Depletion of peripheral blood lymphocytes in CD25+ cells improves the in vitro detection of weak allergen-specific T cells.- Correlation of contact sensitizer potency with T cell frequency and TCR repertoire diversity.- On the role of co-inhibitory molecules in dendritic cell - T helper cell co-culture assays aimed to detect chemical induced contact allergy.- T cell responses to drugs and drug metabolites.- Hypersensitivity reactions to betalactams.