Detailansicht
Epigenomics
ISBN/EAN: 9781402091865
Umbreit-Nr.: 1301581
Sprache:
Englisch
Umfang: xiv, 438 S.
Format in cm:
Einband:
gebundenes Buch
Erschienen am 19.12.2008
Auflage: 1/2009
- Zusatztext
- InhaltsangabePreface/Introduction: Introduction to epigenomics, AC Ferguson-Smith, JM Greally, RA Martienssen; Section I Epigenomic technologies and analytical approaches 1. Strategies for epigenome analysis, AB Brinkman and HG Stunnenberg 2. Sequencing the epigenome, A Meissner and BE Bernstein 3. Integrating epigenomic Results, S-Y Yoo and RW Doerge 4. Visualising the epigenome, P Flicek and E Birney Section II Roles of DNA, RNA and chromatin in epigenomics 5. The expanding view of cytosine methylation, JM Greally 6. Structural and biochemical advances in mammalian DNA methylation, X Cheng and R Blumenthal 7. Epigenetic profiling of histone variants, S Henikoff 8. Epigenetic phenomena and epigenomics in maize, J Hollick and N Springer 9. Epigenetic silencing of pericentric heterochromatin by RNA interference in Schizosaccharomyces pombe, S Locke and RA Martienssen 10. Describing epigenomic information in Arabidopsis, I. Henderson 11. The role of small RNAs in establishing chromatin architecture in Drosophila, J Birchler 12. MacroRNAs in the epigenetic control of X inactivation, S Shibata and JT. Lee Section III Epigenetic control of developmental processes 13. Polycomb complexes and the role of epigenetic memory in development, Y Schwartz and V Pirrotta 14. Genomic imprinting - a model for roles of histone modifications in epigenetic control, K McEwan and AC Ferguson-Smith 15. The epigenomic landscape of reprogramming in mammals, G Ficz, C Farthing and W Reik 16. Epigenetic regulation - lessons from globin loci, A Dean and S Fiering 17. Meiotic silencing, infertility and X chromosome evolution, J. Turner Section IV The epigenome in health and disease 18. Genome defence - the Neurospora paradigm, M Rountree and E Selker 19. Integrating the genome and epigenome in human disease, C Widelius 20. A changing epigenome inhealth and disease, E. Ballestar and M Esteller 21. Cancer epigenomics, C. Ladd-Acosta and A Feinberg 22. Epigenetic modulation by environmental factors, M Doyle and R Amasino 23. The relevance of epigenetics to major psychosis, J Mill and A Petronis Index
- Kurztext
- Epigenomics tells us how the genome worksCharacterising the epigenome is the next big step after determining the sequence of the genomeEpigenetic influences are major causes of diseaseThe epigenome is dynamic and can change in response to both intrinsic and extrinsic cues