Detailansicht
Bortezomib in the Treatment of Multiple Myeloma
eBook - Milestones in Drug Therapy
ISBN/EAN: 9783764389482
Umbreit-Nr.: 1802391
Sprache:
Englisch
Umfang: 180 S., 1.93 MB
Format in cm:
Einband:
Keine Angabe
Erschienen am 20.10.2010
Auflage: 1/2010
E-Book
Format: PDF
DRM: Digitales Wasserzeichen
- Zusatztext
- Multiple Myeloma (MM) is the second most common type of blood cancer, resulting from an overproduction of cancerous infection-fighting white blood cells, known as plasma cells. Plasma cells are a crucial part of the immune system responsible for the production of antibodies. Bortezomib is a promising anticancer drug targeting the proteasome. This proteasome inhibitor induces cell stress and apoptosis in the cancer cells. While multiple mechanisms are likely to be involved, proteasome inhibition may prevent the degradation of pro-apoptotic factors, permitting activation of programmed cell death in neoplastic cells dependent upon the suppression of proapoptotic pathways.This monograph on bortezomib is a valuable source of information for researchers and clinicians from the fields of oncology and pharmacology, working either in academia or the pharmaceutical industry.
- Kurztext
- Multiple Myeloma (MM) is the second most-common blood cancer. Bortezomib is a promising anticancer-drug targeting the proteasome. This monograph on bortezomib is a valuable source of information for researchers and clinicians from oncology and pharmacology.