Detailansicht
Gemini Surfactant-Based Gene Therapy
Non-invasive gene delivery
ISBN/EAN: 9783846581728
Umbreit-Nr.: 3183771
Sprache:
Englisch
Umfang: 240 S.
Format in cm: 1.5 x 22 x 15
Einband:
kartoniertes Buch
Erschienen am 15.02.2012
Auflage: 1/2012
- Zusatztext
- Similar to the majority of biological molecules, DNA is degraded rapidly in the body. Its encapsulation into a delivery system increases circulation time and permits accumulation of the drug in certain organs. Lipid-based soft nanoparticles have the ability to encapsulate or complex DNA and shuttle it into the cells by overcoming cellular and molecular barriers. The use of state-of-the-art technology for the systematic evaluation of the gene transfer efficiency of the novel nanoparticles leads to the development of in vivo gene delivery systems for topical non-invasive administration. These delivery systems find application in the development of new gene therapy for dermatology, immunology/vaccines and neurodegenerative diseases.
- Autorenportrait
- Ildiko Badea, PhD studied Pharmaceutical Sciences in the College of Pharmacy and Nutrition at the University of Saskatchewan, Canada. Marianna Foldvari, PhD is a Canada Research Chair in Bionanotechnology and Nanomedicine and Professor of Pharmaceutical Sciences in the School of Pharmacy at University of Waterloo, Canada.