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CD4+CD25+T cells in HCV patients & Prevalence of Bacterial infection
ISBN/EAN: 9783659293467
Umbreit-Nr.: 4234158
Sprache:
Englisch
Umfang: 160 S.
Format in cm: 1 x 22 x 15
Einband:
kartoniertes Buch
Erschienen am 06.12.2012
Auflage: 1/2012
- Zusatztext
- CD4+CD25+Treg lymphocytes are a subset of circulating CD4+T cells with suppressive properties. CD4+CD25+ Treg cells suppress HCV-specific T cell responses. They may play a role in viral persistence. Our study was designed to assess the frequency of Treg cells as well as occurrence of bacterial infection in different clinical presentation of HCV infection in a chosen Egyptian population. Data obtained showed high significant frequency of CD4+CD25+Treg cells in all HCV patients in comparable to healthy individuals. Conversely, within different clinical degrees of HCV infection no significant differences were detected. Higher Frequency of CD4+CD25+ Treg cells detected in HCV patients than in normal individuals may help to be used as a marker for early detection of viral disease and open new area to find a way to disease recovery/protection. The prevalence of bacterial infection among HCV patients was significant high as detected in both blood and urine samples specially among those with late disease episode. Staphylococcus aureus and -hemolytic Streptococcus viridanse were the common infected organisms in blood samples of HCV patients. In urine samples, Escherichia coli was detected.
- Autorenportrait
- Professor of Microbiology at Suez Canal University, got her MSc dgree in 1986, PhD dgree in 1991 through cooperation between Harvard Univ. and SCU, Associate Prof. in 1997&Prof. in 2003, Head of Botany Dept at SCU in 2009 till May 2012. She is interested in many fields: Medical Micro., Applied Biotechnology, N2 fixation, Actinomyetes& Agro-forestry