Detailansicht
Leishmaniasis and the role of Iron
ISBN/EAN: 9786202005258
Umbreit-Nr.: 2838526
Sprache:
Englisch
Umfang: 64 S.
Format in cm: 0.4 x 22 x 15
Einband:
kartoniertes Buch
Erschienen am 05.09.2017
Auflage: 1/2017
- Zusatztext
- The unicellular kinetoplastid protozoan parasites of genus Leishmania are the causative agents of complex neglected diseases called leishmaniasis and continue to be a significant health concern globally. Chapter 1 provide a brief overview of leishmaniasis and outline the number of drugs available for the treatment along with the possible targeted pathway in Leishmania parasite. The aim of chapter 2 is to provide an update on the current knowledge about iron acquisition and usage by Leishmania species. For the parasite survival and virulence, iron as metal ion plays a crucial role in many facets of cellular metabolism as a cofactor of several enzymes. Iron acquisition is essential for the survival of parasites. Since iron plays central roles in the hosts response and parasite metabolism, a comprehensive understanding of the iron metabolism is beneficial to identify potential viable therapeutic opportunities against leishmaniasis.
- Autorenportrait
- Amir Zaidi, M.Sc. Biochemistry from Jamia Hamdard, New Delhi and Ph.D.(Biochemistry) from University of Calcutta. He studied the Fe-S cluster assembly machinery of model pathogen Leishmania donovani which causes visceral leishmaniasis.