Detailansicht
Peroxisome Proliferator-Activated Receptors
Discovery and Recent Advances
ISBN/EAN: 9781627038867
Umbreit-Nr.: 2876753
Sprache:
Englisch
Umfang: ix, 137 S.
Format in cm:
Einband:
kartoniertes Buch
Erschienen am 22.05.2015
Auflage: 1/2015
€ 117,69
(inklusive MwSt.)
Nachfragen
- Zusatztext
- All three peroxisome proliferator-activated receptor (PPAR) subtypes share a high degree of structural homology while exhibiting differences in function, tissue distribution, and ligand specificity. In Peroxisome Proliferator-Activated Receptors: Discovery and Recent Advances, the authors trace the history of PPAR discovery and detail the receptor structure and its posttranslational modifications. Furthermore, endogenous ligands as well as various classes of exogenous ligands, subtype-selective, dual and pan agonists as well as antagonists, are discussed. In addition, the tissue distribution and versatile functions of PPAR subtypes in major organs are described. As PPARs play critical roles as regulators of numerous physiological as well as pathophysiological pathways, Peroxisome Proliferator-Activated Receptors: Discovery and Recent Advances aims to help researchers to develop safer and more effective PPAR modulators as therapeutic agents to treat a myriad of diseases and conditions.
- Kurztext
- This book reviews the history of PPAR discovery and details receptor structure and its posttranslational modifications, discusses endogenous and exogenous ligands, the tissue distribution and versatile functions of PPAR subtypes in major organs and much more.